Preterm birth PTB is one of the most common complications during pregnancy and it primarily accounts for neonatal mortality and numerous morbidities including long-term sequelae including cerebral palsy and developmental disability. The most effective treatment of PTB is prediction and prevention of its risks.
inaccurate administration dose Vaginal progesterone
J Perinat Med. The risk factors of PTB include history of PTB, short cervical length CL , multifetal pregnancy, advanced maternal age, infectious diseases, genetic factors, smoking, uterine anomaly, and history of curettage or cervical conization [ 4 ]. Because vaginal progesterone has a half-life of approximately 13 hours, 77 it should be administered daily.
Obstet Gynecol Sci. No side effects have been reported as far as lipid profile, coagulation factors and blood pressure are concerned.